http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201718513-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f52c68e4149a6c462b850d4e7cc2b2f9 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-13 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D235-30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-4184 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D235-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4184 |
| filingDate | 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6ddb72f519c4ff6d10d084388f14d10 |
| publicationDate | 2017-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201718513-A |
| titleOfInvention | Method for preparing substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propionic acid derivative |
| abstract | The present invention relates to a process for the preparation of a substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propionic acid derivative of the general formula (I) wherein R1 represents hydrogen The atom or R1 represents a group selected from the group consisting of C1-C3 alkyl-, C1-C3 alkoxy-, C1-C3 haloalkyl-, and C1-C3 haloalkoxy-, and R2 represents a hydrogen atom or C1- C3 alkyl, R3 represents a hydrogen atom or a C1-C3 alkyl group, R4 represents a cyclohexyl group, which may be mono- or polysubstituted by a C1-C3 alkyl group, and R5 represents a hydrogen atom or a C1-C6 alkyl group; An intermediate of the substituted 3-(2-anilino-1-cyclohexyl-1H-benzimidazol-5-yl)propionic acid derivative is prepared. The present invention also relates to 3-(2-{[4-(trifluoromethoxy)phenyl]amino}-1-[(1R,5R)-3,3,5-trimethylcyclohexyl]-1H a crystalline form of -benzimidazol-5-yl)propionic acid, a pharmaceutical composition comprising the crystalline form, and the use of the crystalline form for the preparation of a medicament for treating a disease. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I760017-B |
| priorityDate | 2015-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 588.