| abstract |
The present invention provides a disease associated with Nav1.7, specifically neuropathic pain, nociceptive pain, inflammatory pain, fibrotic neuropathy, acromegaly, paroxysmal pain, dysuria or multiple A therapeutic drug for diseases such as sclerosis. The present invention provides a compound or a pharmaceutically acceptable salt thereof, which is represented by the formula (I): □ [wherein, R1an, R1bn, R1cnAnd R1dnRepresents hydrogen, halogen, cyano, C1-4nAlkyl, C1-4nAlkoxy group, etc., of which R1an, R1bn, R1cnOr R1dnAt least one of them represents C6-10nAryl, C6-10nAryloxy, etc., R2nAnd R3nRepresents hydrogen, C1-6nAlkyl, C3-10nCycloalkyl, etc., R4nRepresents hydrogen, C1-6nAlkyl, C3-7nCycloalkyl, etc., m represents 1, 2 or 3, and L represents CR7nR8n, R7nAnd R8nRepresents hydrogen, hydroxyl, C1-4nAlkyl, C1-4nAlkoxy group, etc.]. |