| abstract |
The present invention relates to a guanamine-substituted cyclohexane compound of the formula (I):nâ–ˇnWherein A, R4, R6, R7, R8, R9, R10 and R11 are as defined herein; a method of preparing the compounds; an intermediate compound suitable for the preparation of the compounds; a pharmaceutical composition and combination comprising the compounds; The use of such compounds as separate agents or in combination with other active ingredients for the manufacture of a pharmaceutical composition for the treatment or prophylaxis of diseases, in particular, neoplasms. |