abstract |
The present invention relates to a site-specific homogeneous binding agent drug conjugate of a spindle kinesin inhibitor, an active metabolite of the conjugate, a method of preparing the conjugate, and the conjugate is used for treatment and/or prevention Uses of diseases, and the use of such combinations for the preparation of a medicament for the treatment and/or prophylaxis of diseases, in particular hyperproliferative and/or angiogenic disorders, such as cancer. Such treatments can be performed as a monotherapy or in combination with other agents or other therapeutic measures. |