abstract |
Described herein are binding proteins that specifically bind to human CD33, and in particular bispecific binding proteins that specifically bind to human CD33 and human CD3. Also described herein are bispecific tandem bifunctional antibodies (diabodies) that bind to CD33 and CD3 and their use for immunotherapy of CD33+ cancers, diseases and conditions, such as acute myeloid leukemia (AML). |