abstract |
The present invention provides a substituted benzoxa- boron having a structure comprising Formula III,nWherein R3 is selected from the group consisting of -CH3, -CH2CH3, -CH2=CH2, -CH2CH2CH3, -CH(CH3)2, -CH2CH2=CH2, and cyclopropyl, and R1 and R2 are each independently selected from H, -CH3, - CH2CH3, -CH2CH2CH3 and -CH(CH3)2; compositions containing such compounds; their use in therapy, including their use as antimycobacterial agents, for example for the treatment of mycobacterial infections in mammals And methods for preparing such compounds. |