| abstract |
The present invention discloses to treat or reduce symptoms or diseases caused by menopause in postmenopausal women [in particular, osteoporosis, vaginal atrophy and dryness, gonadal dysfunction, in susceptible warm-blooded animals (including humans), Loss of libido, skin atrophy, connective tissue disease, urinary incontinence, breast cancer, endometrial cancer, ovarian cancer and uterine cancer, hot flashes, loss of muscle mass, insulin resistance, fatigue, loss of energy, aging, and menopause A novel method of the possibility of physical symptoms, which involves the administration of a sex steroid precursor. The method comprises a novel means of administering and administering dehydroepiandrosterone (DHEA), which utilizes positive androgenic effects in the lamina propria and/or muscle layers of the vagina without undesired Causes systemic estrogen effects to avoid the risk of breast cancer and uterine cancer. The invention also discloses pharmaceutically acceptable compositions for the delivery of active ingredients (etc.) useful in the present invention. |