abstract |
This article reports humanized anti-IL-1β antibodies, which are humanized variants of the murine anti-IL-1β antibody H34. A specific humanized antibody comprising (a) HVR-H1 comprising the amino acid sequence SEQ ID NO: 25; (b) HVR-H2 comprising the amino acid sequence SEQ ID NO: 27; and (c) comprising an amine group Acid sequence HVR-H3 of SEQ ID NO:28. |