| abstract |
Compound of formula I:n□ and its stereoisomers and pharmaceutically acceptable salts and solvates are inhibitors of one or more JAK kinases and are useful in the treatment of JAK kinase-related diseases and conditions, such as autoimmune diseases, inflammatory diseases, Transplanted organs, tissues and cell rejection as well as hematological and malignant diseases and their co-occurrence, wherein R1, R2, R3 and R4 have the meanings provided in the present specification. |