abstract |
The invention comprises a compound of formula In□nWherein: X, A1, A2, A3, A4, R1, R2, and R3 are defined in the specification.nThe invention also encompasses a method of treating or ameliorating a syndrome, disorder or disease, wherein the syndrome, disorder or disease is rheumatoid arthritis or dryness. The invention also encompasses a method of modulating RORyt activity in a mammal by administering a therapeutically effective amount of at least one compound as described in claim 1 of the patent application. |