abstract |
The present application relates to novel substituted piperidinylpyrazolopyrimidones, to a process for their preparation, to a method for treating and/or preventing a disease, alone or in combination, in a method, particularly for the treatment and/or prophylaxis with or without Acute and recurrent hemorrhage in patients with underlying hereditary or acquired coagulopathy, which is associated with a disease or medical intervention selected from the group consisting of: menstrual bleeding, postpartum blood loss, hemorrhagic shock, hemorrhagic bladder Inflammation, gastrointestinal bleeding, trauma, surgery, transplantation, stroke, liver disease, hereditary angioedema, nosebleeds, synovitis and cartilage damage after joint blood. |