abstract |
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyridin-4 as a negative sex regulator (NAM) of metabotropic glutamate receptor subtype 2 ("mGluR2") (5H)-keto derivative. The present invention is also directed to pharmaceutical compositions comprising such compounds, to methods for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of mGluR2 subtypes in which metabotropic receptors are involved. The use of obstacles. |