abstract |
The present invention relates to a series of fused bicyclic heteroaromatic derivatives of formula (IA) or (IB) as defined herein as a selective inhibitor of phospholipid cyclohexanol-4-kinase IIIβ (PI4KIIIβ) activity It is beneficial for the treatment and/or prevention of a variety of human diseases, including inflammatory, autoimmune and neoplastic disorders; viral diseases and malaria; and organ and cell transplant rejection. |