| abstract |
a compound of formula (I),nâ–ˇnAnd a pharmaceutically acceptable salt thereof or a radiolabeled form, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12 and m are as defined in the specification, which is useful for Treatment of a condition or disorder prevented or ameliorated by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) protein. The present invention describes methods of preparing such compounds, as well as pharmaceutical compositions of the compounds of formula (I) and methods of using such compounds and compositions. |