| abstract |
The present invention relates to an antibacterial compound of formula In□ wherein R1 is a group M, wherein M is one of the groups MA and MB represented below:n□ where A is a bond or C≡C; R1A is H or halogen; R2A is H or halogen; R3A is H, alkoxy, hydroxyalkoxy, hydroxyalkyl, dihydroxyalkyl, 2-hydroxyacetamide Substituted, substituted cycloprop-1-yl or substituted oxetan-3-yl; and R1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, dialkylaminoalkyl, substituted ring Prop-1-yl, substituted cyclobutene-1-nSubstituted, substituted oxetan-3-yl, 3-hydroxythietin-3-yl, substituted azetidin-3-yl, trans-(cis-3,4-dihydroxy) -cyclopent-1-yl, 3-hydroxymethylbicyclo[1,1,1]pentan-1-yl, 4-hydroxytetrahydro-2H-pyran-4-yl, (3R,6S)-3 -Aminotetrahydro-2H-pyran-6-yl, hexahydropyridin-4-yl or 1-(2-hydroxyethyl)hexahydropyridin-4-yl; and salts thereof. |