http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201619129-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fe511b4e57c11304f1eff2dd62fc86b5 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-40 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-15 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D207-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D207-48 |
| filingDate | 2015-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fc0096ee508a887778e9acf718ba1f30 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3fe7c5a934a31471b40d5fa1fcbfebb5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_04aadbb77cb5c0d13916b26aed8f8caa |
| publicationDate | 2016-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201619129-A |
| titleOfInvention | Semi-fumarate containing pyrrole ring proton pump inhibitor and its crystal form, intermediate and medical use |
| abstract | The present invention discloses hemifumarates containing a pyrrole ring proton pump inhibitor, crystalline forms and intermediates thereof, and medical uses. Specifically, the present invention relates to a hemifumarate, a crystalline form, an intermediate, a preparation method thereof and a medical use of a proton pump inhibitor containing a pyrrole ring, that is, 2-(3-(()) represented by the formula (I) 2-(2-Fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)phenoxy)-N-methylacetamide semi-fumaric acid a salt, and by 2-(3-((2-(2-fluorophenyl)-4-((methylamino)methyl)-1H-pyrrol-1-yl)sulfonyl)phenoxy) a method of salt formation of -N-methylacetamide with fumaric acid and characterizing the crystalline form of hemifumarate. The hemifumarate of the present invention and its crystal form are more stable, exhibit excellent biological activity, and have good gastric acid inhibition.n□ |
| priorityDate | 2014-11-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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