http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201617456-A
Outgoing Links
Predicate | Object |
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assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fb65ab1b41c2067a40270436dc55a429 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-156 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6858 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6818 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-68 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2015-07-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0bc6bb05aeb7ae981ddcebc3490e531e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a75b7bd22bf6f9689cd916b0ef9f51a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_02033e344a85f1719a749599921edd2e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c462dbca9c1a01a3c49c26f4c4b055e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fc5a70ec39db8c599bc81501406556b |
publicationDate | 2016-05-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201617456-A |
titleOfInvention | Application of multi-target nucleic acid detection method using clamping probe and detection probe |
abstract | The invention relates to the application of a target nucleic acid detection method using a clamp probe and a detection probe, which can selectively amplify and detect a very small amount to be detected by inhibiting amplification of a wild-type gene or an unnecessary gene. The target gene is used to efficiently detect trace amounts of mutations or specific gene sequences contained in the sample. Moreover, multiple genotypes can be identified simultaneously by melting curve analysis. In particular, methods for diagnosing, prognosis, monitoring, evaluation of therapeutic efficacy, methods of nucleic acid and protein transduction, and the like for medical morbidity of diseases can be used by a very small number of mutant genotypes identified as high detection sensitivity.nThe present invention includes the use of invasive specimens such as tissue and non-invasive specimens (blood, urination, sputum, stool, saliva, cells) to detect epidermal growth factor receptor (EGFR), Kirsten rat sarcoma virus oncogene homologs (KRAS), a biomarker such as a neuroblastoma virus oncogene (NRAS) and a step of evaluating the presence of a mutation in a biomarker, the presence of the above biomarkers and mutations providing for detection of disease in the life cycle of the disease in question The prognosis, the prediction, the treatment policy for determining the disease, the diagnosis/early diagnosis of the disease, the prevention of the disease, and the method used in the development of the therapeutic agent for the disease. |
priorityDate | 2014-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 469.