http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201615836-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_461514df460e0cdd5644e86ba60adbf7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_35f1bf7625ec038f633e972977ad7a70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N5-074 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N11-14 |
| filingDate | 2014-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e68c4d01695f6ba1f7cbde979cc9f7a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c095f154b75abb1351ecc54d8ebbef7a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0d12647e975f14b235553af75b7b6929 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e224915e4ef8c4d8436d76e8fb594624 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aad9cb2ba208f741c8abb7ba55a1d051 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_002fe7e2a9755029d05fbe52dc062b09 |
| publicationDate | 2016-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201615836-A |
| titleOfInvention | Method for promoting the transfer of biologically active substances into cells |
| abstract | The present invention provides a method for promoting the transfer of a biologically active substance into a cell, comprising: providing a nano substrate, wherein the nano substrate is disposed on a surface of a bottom plate; providing a cell and containing a substance to be delivered into the cell a solution of the biologically active substance; and seeding the cell on the nano substrate and adding a solution of the biologically active substance to be delivered into the cell. The surface morphology of the nano substrate of the invention can rearrange the cytoskeleton of the cell, so that the carrier can be moved and the biological active substance can be swallowed without the need of a carrier or a transfection reagent, thereby achieving the transfer and shortening of the nuclear biological active substance. The time required. Compared with the traditional method, it can not only reduce cytotoxicity, but also increase the efficiency of delivery. |
| priorityDate | 2014-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 239.