abstract |
The present invention relates to novel substituted (aza)pyridopyrazolopyrimidinones and oxazolopyrimidinones, a process for the preparation thereof, a compound for use in a method for treating and/or preventing a disease, alone or in combination, Particularly for treating and/or preventing acute and recurrent bleeding in a patient with or without a potential hereditary or acquired bleeding disorder, wherein the bleeding is associated with a disease selected from the group consisting of Medical intervention related: menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver disease, hereditary angioedema, nosebleeds and synovitis and cartilage damage after joint hemorrhage. |