abstract |
The present invention discloses a carbazole compound of the formula (I) as a cyclin-dependent kinase (CDK) and a cell proliferation inhibitor, and a medical use thereof and a preparation method. Such compounds and their pharmaceutically acceptable salts, solvates, prodrugs and pharmaceutical compositions are suitable for the treatment of diseases and conditions associated with the activity of cyclin-dependent kinases, particularly CDK4/6, such diseases and conditions Contains, but is not limited to, various cancers and inflammation-related diseases or conditions.n□ |