| abstract |
This article discloses compounds of formula (I)n□ or a salt thereof, wherein: HET is a heteroaryl group selected from the group consisting of pyrazolyl, fluorenyl, pyrrolo[2,3-b]pyridyl, pyrrolo[2,3-d]pyrimidinyl, pyridyl Zoxao[3,4-b]pyridyl, pyrazolo[3,4-d]pyrimidinyl, 2,3-dihydro-1H-pyrrolo[2,3-b]pyridyl, imidazo[4 , 5-b]pyridyl and indenyl, wherein the heteroaryl is substituted by Ra and Rb; and R1 and R2 are as defined herein. Also disclosed herein are methods of using such compounds as modulators of IRAK4, and pharmaceutical compositions comprising such compounds. These compounds are useful in the treatment, prevention or alleviation of inflammatory and autoimmune diseases. |