abstract |
The invention discloses an aromatic heterocyclic derivative and its application in medicine, in particular, the invention provides an aromatic heterocyclic compound or a stereoisomer, a geometric isomer, a tautomer thereof and a racemate thereof. , nitrogen oxides, hydrates, solvates, metabolites, pharmaceutically acceptable salts or prodrugs, and pharmaceutical compositions containing the compounds of the invention. The invention also discloses the use of a compound of the invention or a pharmaceutical composition thereof for the preparation of a medicament for the treatment of respiratory diseases, in particular chronic obstructive pulmonary disease (COPD). |