abstract |
The present invention provides a compound which is useful as a pharmaceutical composition, particularly as an active ingredient of a pharmaceutical composition for the prevention and/or treatment of a VAP-1 related disease.nThe inventors of the present invention conducted a detailed review of compounds having VAP-1 inhibitory activity, and found that the compound of the present invention or a salt thereof exhibits excellent VAP-1 inhibitory activity, and is associated with VAP-1 associated diseases, particularly diabetic kidney disease or diabetic macula. The present invention has been accomplished in terms of prevention and/or therapeutic use of edema. Further, the present invention relates to a pharmaceutical composition comprising the compound of the present invention or a salt thereof and an excipient, and particularly to a pharmaceutical composition for use in the prevention and/or treatment of a VAP-1 related disease. |