abstract |
The subject matter herein is a carbazole-containing guanamine, a urethane, and a urea derivative of the formula I, and a pharmaceutically acceptable salt or hydrate thereof, wherein the variables R1, R2, R3, R4, R5, R6, R7, A, D, E, G, J, L, M, Q, a, and b are described accordingly. Pharmaceutical compositions containing a compound of formula I are also provided for the treatment of Cry vector diseases or disorders such as diabetes, diabetes-related complications, Cushing's syndrome, NASH, NAFLD, asthma, and COPD.n□ |