abstract |
The present invention relates to a PYY compound having a tryptophan-substituted amino acid in a position corresponding to position 30 of hPYY(1-36) and a derivative thereof, which have an attachment to hPYY (1) -36) A modifying group at position 7 of position 7. The compounds of the invention are selective Y2 receptor agonists. The invention also relates to pharmaceutical compositions comprising such PYY compounds and pharmaceutically acceptable excipients, and to the medical use of such PYY compounds. |