| abstract |
The present invention provides a performance-regulating agent for a clock gene which has a rich edible experience and is highly safe, easy to obtain, and has excellent processability.nThe expression-regulating agent for the clock gene of the present invention is effective as a compound selected from the group consisting of oleuropein, 3,4-DHPEA-EA, and derivatives thereof, and salts thereof ingredient. The expression regulator of the clock gene of the present invention reversely regulates the expression levels of the Per1 gene and the Bmal1 gene, whereby the performance rhythm of the Per gene and the Bmal gene can be adjusted to the normal direction. |