| abstract |
The present invention relates to pharmaceutical agents useful for treatment and/or prevention in mammals, and in particular to inhibitors of NF-κB-induced kinase (NIK-also known as MAP3K14), which are useful in the treatment of Diseases such as cancer, inflammatory conditions, metabolic disorders, and autoimmune disorders. The present invention is also directed to pharmaceutical compositions comprising such compounds; to methods of preparing such compounds and compositions; and to the use of such compounds or pharmaceutical compositions for the prevention or treatment of diseases such as cancer, inflammatory Disorders, metabolic disorders including obesity and diabetes, and autoimmune disorders. |