| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_59e1d955a7b1560dc68cf7fd800e8fac
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_305de2905adc4dec4673da14e30921b8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-505
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-567
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-56
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-565
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-55
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-33
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-24
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-732
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-94
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-77
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-92
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-76
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-734 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-3023 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
| filingDate |
2014-06-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c806b6b36af887a5d4261666cf26adee
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff838587f717f83c38ba211a3beaa079
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9276faa285ce13b4a05d94ae0ab2f1cb
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1ff0ec9a79aabc2d24ef7ed27c298ef
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a362021430a2c3430eb3be7ced0e241d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_178c80c8561205b5bd7bde04fa7d7619 |
| publicationDate |
2015-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201542591-A |
| titleOfInvention |
A therapeutic agent for non-small cell lung cancer other than adenocarcinoma containing a humanized anti-Epiregulin antibody as an active ingredient |
| abstract |
The present inventors succeeded in substituting an amino acid residue in the sequence of the variant region of the humanized EP27 antibody which inhibits cancer cell proliferation by exerting cytotoxicity and neutralizing activity on cancer cells expressing human Epiregulin. Anti-Epiregulin antibody showing cross-reaction between species of crabs and humans in non-human animals, anti-Epiregulin antibody with suppressed chemical decomposition, anti-Epiregulin antibody with decreased isoelectric point, and anti-Epiregulin with elevated temperature at heat denaturation An anti-Epiregulin antibody having a reduced amount of an antibody or an association is successfully used as a therapeutic agent for non-small cell lung cancer other than adenocarcinoma containing the antibody as an active ingredient. |
| priorityDate |
2013-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |