| abstract |
The present invention provides a novel method of reducing the amount of serine protease and/or serine proproteinase derived from plasma-derived protein compositions. Also provided are methods of making a plasma-derived protein composition having reduced levels of serine protease and/or serine proproteinase. In other aspects, the invention provides aqueous and lyophilized compositions of plasma-derived proteins having reduced levels of serine protease and/or serine proproteinase. Other aspects include methods of treating, treating, and/or preventing a disease comprising a plasma-derived protein composition administered with a reduced amount of a serine protease or a serine proproteinase. |