| abstract |
The present invention relates to a droplet actuator device and test method for testing metabolic disorders in multiplexed newborns. These methods include, inter alia, droplet-based enzyme assays and immunoassays for testing metabolic disorders. The invention includes multiple trials of different metabolic disorders on a single droplet actuator, and the use of samples from different individuals and/or multiple samples from the same individual on a single droplet actuator for the same metabolic disorder Method and apparatus for multiple trials. In various embodiments, the invention includes methods of performing enzyme activity assays and/or immunoassays in a single fresh blood and/or plasma sample and dried blood and/or plasma samples. |