| abstract |
The present invention discloses a compound of formula I,n□ wherein R1, R2, R3, R4, L and X are as defined herein.nThe present invention relates to a compound, a process for producing the same, a pharmaceutical composition comprising the same, and a method for preventing and/or treating an inflammatory condition, type 2 diabetes, a neurological disease and/or a neurodegenerative disease, an autoimmune disease, Proliferative diseases (especially metastatic diseases and/or cancers), diseases associated with abnormal angiogenesis, cartilage degradation and/or cartilage homeostasis, in particular for the prevention and/or treatment of cancer. The invention also discloses methods of treatment using such compounds by administering the compounds of the invention for the prevention and/or treatment of such diseases. |