http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201529598-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3120ae9cab5bb4831f0cc16288966367 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-575 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-22 |
| filingDate | 2014-07-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_64b6310b715a10c7152b4c34e157d25e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b871240a4ba6906d699f4c20141eb5a1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51edee2553c908b7c9e2b2507d7fa0d3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6aa2fa2fb7a2179a02e7569572b33ff0 |
| publicationDate | 2015-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201529598-A |
| titleOfInvention | Derivatives of GLP-1 peptides and uses thereof |
| abstract | The present invention relates to derivatives of the GLP-1 peptide, which are C-terminal extension analogs of native GLP-1. The derivatives comprise two side chains, one at a position corresponding to position 42 and one at a position corresponding to position 18, 23, 27, 31, 36 or 38, both of which are associated with GLP-1 ( 7-37) compared. The side chains comprise a C19, C20 or C22 diacid extension and, optionally, a linker. The invention also relates to intermediates in the form of novel GLP-1 analogs incorporated into derivatives of the invention, as well as pharmaceutical compositions and medical uses of such derivatives. These derivatives have an extremely long half-life while maintaining satisfactory performance, thereby making them potentially suitable for once-monthly administration. |
| priorityDate | 2013-07-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 685.