http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201521793-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_382ccfc2ebebcaee15aa7cda4cee86bc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2018 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20 |
| filingDate | 2014-04-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8da2ddba980eb8671f47fec152d001f4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b4ba46f6bd6fde154d76d3c32c9032da http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e45c7f5ffe6388d8ec6c453c5ee2b17a |
| publicationDate | 2015-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201521793-A |
| titleOfInvention | Oral solid preparation containing aripiprazole, and method for producing oral solid preparation containing aripiprazole |
| abstract | An object of the present invention is to provide an oral solid preparation which can be produced by a simpler method than before, and which has high bioavailability and high dissolution even for low stomach acid, and further ensures a certain period of time after standing. Dissolution property, and a simple manufacturing method for producing the oral solid preparation. The present invention relates to an orally solid preparation comprising finely pulverized crystals obtained by pulverizing a crystal of aripiprazole as an active ingredient, and a pharmaceutically acceptable carrier, wherein the average particle diameter of the finely pulverized crystal is 15 μm or less; an orally solid preparation containing a finely pulverized powder obtained by pulverizing an aripiprazole anhydrate having high hygroscopicity as an active ingredient, and a pharmaceutically acceptable carrier, and an average particle diameter of the finely pulverized powder The method for producing an orally solid preparation comprises (1) pulverizing a crystal of aripiprazole hydrate to obtain a finely pulverized crystal having an average particle diameter of 15 μm or less, and (2) finely pulverizing the obtained granule. a step of mixing crystals with a pharmaceutically acceptable carrier; and a method for producing an orally solid preparation comprising (1') pulverizing a highly hygroscopic aripiprazole anhydrate to obtain an average particle diameter of 10 μm or less a step of pulverizing the powder, (2') a step of mixing the obtained finely pulverized powder with a pharmaceutically acceptable carrier. |
| priorityDate | 2013-04-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 39.