http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201504436-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_943d21326a8034afdb808ab726293c7d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_051f9620a6e82f6e316aef1e4b9a5711 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C40B20-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate | 2013-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd117925cd75c80f7116c101e2978c21 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb6bf70f994a01566cd2dcb522bf1e38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e5e0dc616de4aa7842b9720a4485c963 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_57c6482abf34a5d5195c996ce76cf1fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bfffac1b225e34a3a2778ec0ba84b66a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea5a1515fb6652af9f21f5551cbca7e3 |
| publicationDate | 2015-02-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201504436-A |
| titleOfInvention | Environmental and epigenetic-based oral cancer screening methods in vitro |
| abstract | The invention provides an environmental and epigenetic-based oral cancer screening method in vitro, comprising: providing a dental specimen derived from a subject and a control sample; determining the oral sample and the control The degree of methylation of the CpG sequence of the paired box gene 1 (PAX1) and the sex-determining region Y-box 1 (SOX1) in the specimen; when the subject For the betel nut chew, and the degree of methylation of PAX1 derived from the oral sample of the subject is higher than that of the control sample; and/or the degree of methylation of SOX1 derived from the oral sample of the subject The subject is at risk of developing oral cancer when compared to the control sample. Since the subject's specimen can be easily obtained in a non-invasive manner, and the DNA methylation detection method is highly sensitive and specific for precancerous lesions, the method of the present invention has great advantages for detecting oral cancer. |
| priorityDate | 2013-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 116.