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filingDate 2013-09-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa0f602191dcbf5ecb117683fd09753c
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publicationDate 2015-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-201502507-A
titleOfInvention Analytical method for detecting sulfated oligosaccharides
abstract The present invention describes the detection and quantification of polysulfated oligosaccharides using a hydrophilic interaction ultra-high performance liquid chromatography (HILIC-UPLC) coupled to a charged aerosol detector (CAD) or mass spectrometer (MS). Including the analytical method of Fondaparinux sodium. This analytical method provides in-process control in the total synthesis of highly sulfated oligosaccharides by means of separation, quantification and mass identification. Systems and conditions for using such methods are also provided.
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