| abstract |
The present invention relates to antibodies and fragments thereof having binding specificity for HGF. Another embodiment of the invention pertains to the antibodies and binding fragments thereof described herein, comprising the sequences of the VH, VL and CDR polypeptides described herein, and polynucleotides encoding the same. The invention also encompasses combinations of anti-HGF antibodies and binding fragments thereof that bind to one or more functional or detectable moieties. The invention also encompasses methods of making such anti-HGF antibodies and binding fragments thereof. Embodiments of the invention also relate to the use of anti-HGF antibodies and binding fragments thereof for the diagnosis, evaluation and treatment of diseases and conditions associated with HGF. |