| abstract |
The present invention relates to methods and compositions for therapeutic and diagnostic use in the treatment of diseases and conditions caused or related to amyloid or amyloid-like proteins, including amyloidosis, a group and Amylin-like disorders and abnormalities, such as Alzheimer's disease. The present invention provides novel methods and compositions comprising highly specific and highly potent antibodies having the ability to specifically recognize and bind to a particular epitope of a range of beta-like starch proteins. The antibodies obtained by the teachings of the present invention are particularly useful for the treatment of diseases and conditions caused or related to amyloid or amyloid-like proteins, including amyloidosis, a group of diseases and conditions associated with the formation of amyloid plaques, including Secondary amyloidosis and age-related amyloidosis, including but not limited to neurological conditions such as Alzheimer's disease (AD). |