| abstract |
The present invention relates to a compound of the formula 1, 2 or 3: wherein □ is N or -CR0-, wherein R0 is hydrogen, a C1-C6 linear or branched alkyl group, and Z is -CRe- or -N - wherein Re is hydrogen, C1-C6 linear or branched alkyl, etc.; R1 is hydrogen, C1-C6 linear or branched alkyl; R2 is independently hydrogen or C1-C6 linear Or branched alkyl; R3 and R4 are independently hydrogen, C1-C6 linear or branched alkyl; R5 and R6 are independently hydrogen or C1-C6 linear or branched alkyl; R8 Is hydrogen, C1-C6 linear or branched alkyl, etc.; R9 and R10 are independently hydrogen or C1-C6 linear or branched alkyl; Q is -CO-, -(CH2)q- , -(CHRs)q- or -(CRsRt)q-, wherein Rs and Rt are independently a C1-C6 linear or branched alkyl, aryl, alkaryl, heteroaryl or alkaryl; Wherein q is 0, 1, 2 or 3; and wherein n is 0, 1, 2, 3, 4 or 5; or a pharmaceutically acceptable salt thereof, the invention relates to a composition comprising such a compound; Such compounds are useful in the treatment of a variety of diseases, particularly those that are affected by ordinal receptors or mediated by androgen receptors. |