abstract |
The present invention relates to a thioaryl derivative of the formula 1, a process for producing the thioaryl derivative, and a pharmaceutical composition of the thioaryl derivative and use thereof. The thioaryl derivative of the formula 1 of the present invention promotes the formation of GLP-1 in the gastrointestinal tract and improves insulin resistance in macrophages and pancreatic cells due to anti-inflammatory action, and the like, and thus can be effectively used For the prevention or treatment of diabetes, diabetic complications, inflammation, obesity, nonalcoholic fatty liver, steatohepatitis or osteoporosis. □ wherein A, B, D, E, F, G, H, I, J, K, M, R1, R2, R3, R4, R5, R6, R7 and n are defined herein. |