| abstract |
The present invention discloses a composition comprising at least one polymyxin or a salt thereof as shown in formula (I): wherein R1 is an aliphatic straight or branched C6-C10 fluorenyl group or □R5 is -CH (CH3) 2, -CH2CH(CH3)2, -CH(CH3)CH2CH3 or -CH2C6H5; R6 is -CH(CH3)2, -CH2CH(CH3)2 or -CH(CH3)CH2CH3; R2, R3, R4, R7 And R8 are each -(CH2)xCH2NH2 or -(CH2)xCH2N(CH2SO3M)2; wherein x is 0 or 1; wherein M is a monovalent cation; and wherein at least three of R2, R3, R4, R7 and R8 are -(CH2)xCH2N(CH2SO3M)2. |