abstract |
The present invention provides novel methods of treating neuroendocrine tumors. In one embodiment, the method comprises administering to a subject in need of treatment for a neuroendocrine tumor a therapeutically effective amount of a Wnt antagonist. In one embodiment, the Wnt antagonist is an anti-FZD antibody. In another embodiment, the Wnt antagonist is a soluble FZD receptor polypeptide. In still another embodiment, the Wnt antagonist is an anti-Wnt antibody. |