| abstract |
The present invention provides an injectable formulation for intramuscular or subcutaneous administration for the prevention or treatment of polycystic kidney disease, and a blood concentration thereof which can effectively maintain the therapeutic effect of tolvaptan for a long period of time; And its manufacturing method. More specifically, the present invention relates to an injectable reconstituted formulation comprising (1) an optically active tolvaptan-containing granule as an active ingredient, and (2) a pharmaceutically acceptable carrier for injection, and Production method. |