| abstract |
The present invention relates to an ethynyl derivative of the formula I or a pharmaceutically acceptable acid addition salt, racemic mixture thereof or the corresponding enantiomers and/or optical isomers and/or stereoisomers thereof, Wherein Y is N or CH, and R1 is fluorine or chlorine. It has now surprisingly been found that the compounds of formula I are useful in the treatment of anxiety and pain, depression, Fragile-X syndrome, autism series disorders, Parkinson's disease and the stomach. Metabotropic glutamate receptor antagonist (negative allosteric modulator) of esophageal reflux disease (GERD). |