abstract |
The present inventors have found that siRNA which inhibits the expression of the CHST15 gene exhibits a therapeutic effect on Crohn's disease or ulcerative colitis by an experiment using a mouse model of colitis. That is, it has been found that siRNA which inhibits the expression of the CHST15 gene is a mucosal healing promoter, particularly a therapeutic agent for Crohn's disease or ulcerative colitis, and the present invention has been completed. |