abstract |
The present invention provides a novel sulfonamide compound having a TRPM8 blocking effect and useful as a medicine. Specifically, the present invention provides a sulfonamide compound represented by the formula (I) or a pharmacologically acceptable salt thereof. □ [wherein, ring A is of the following formula (i), (ii), or (ix): □ R4 is a substitutable alkyl group, and X1 and X2 are each independently a tetrazolyl group, a tetrazolinone group, Substitutable triazolyl, triazolinone, oxadiazolone, substituted alkylalkylaminomethyl, or substituted alkylsulfonylaminomethyl, or R4 And X2 is bonded to each other at the terminal to form an oxazolinone group or a benzoisoxazolon group, and other symbols are as described in the specification. |