http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201416437-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b765b53e6651e9863a3a35e4c1e164 |
classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-906 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B82Y5-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S977-811 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-48721 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12M33-00 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-42 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/B82Y5-00 |
filingDate | 2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b83df704eb630a1acc3589f49e0172ec http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_77d1ee0c005c34e9ac005fa8a0ed8ac7 |
publicationDate | 2014-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201416437-A |
titleOfInvention | Nano electrode wafer |
abstract | The present invention provides a nanoelectrode wafer that can be applied to locally electroporate a cell membrane of a single cell to allow microfluidic substances to enter a single cell. The nano electrode wafer comprises a ruthenium base layer, a structural layer, an insulating layer and a microfluidic layer. When a single cell is placed on a pore between a plurality of nanoelectrodes that have generated at least one electric field, an electric field acts on a single cell to locally electroporate a cell membrane of a single cell to produce a plurality of nanopore, followed by a microfluidic substance. (eg drugs, DNA molecules, etc.) will flow into a single cell via a small well. The invention not only effectively and precisely controls the size of the pores in the cell membrane, but also clearly provides a path for subsequent optical observations to track the entry of microfluidic substances into a single cell. |
isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11105765-B2 |
priorityDate | 2012-10-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 29.