| abstract |
The present invention relates to a scaffold domain protein which binds to myostatin, which is mainly fibronectin. The invention also relates to the treatment of muscular dystrophy, cachexia, sarcopenia, osteoarthritis, osteoporosis, diabetes, obesity, COPD, chronic kidney disease, heart failure, myocardial infarction and fibrosis in therapeutic applications. use. The invention further relates to cells comprising the proteins, polynucleotides encoding the proteins or fragments thereof, and vectors comprising polynucleotides encoding the proteins. |