http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201416353-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_ada68032e6c5599de33d868231aaa52d |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D227-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D221-18 |
| filingDate | 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c98116fe122f08d1bb16d7eb0e133f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_650d2e5fb39e24fe4cf5bc222fa570d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_55e44a87854a62c183018c3bfd472c58 |
| publicationDate | 2014-05-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201416353-A |
| titleOfInvention | Method for preparing keto apophenin alkaloid |
| abstract | The invention provides a method for preparing a keto-apren alkaloid, which comprises using a cinnamic acid compound as a starting material, the starting material is cyclized to form an iodoisoquinoline compound, and the iodoisoquinoline compound is further prepared. Substituting a nucleophilic aromatic substitution reaction to form an α-cyano-1'-(2"-bromobenzyl)isoquinoline compound, the α-cyano-1'-(2"-bromobenzyl group An isoquinoline compound is oxidatively decyanolated to form a 1'-(2"-bromobenzoinyl)isoquinoline compound; the 1'-(2"-bromobenzoinyl)isoquinoline compound is subjected to After reduction, the keto-apren alkaloid containing different substituents can be synthesized by directly cyclizing with light without further purification. The photocyclization precursor of the preparation method of the present invention can be shortened without purification. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114558012-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-114558012-B |
| priorityDate | 2012-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 153.