| abstract |
The present invention relates to a liquid preparation of a combination of a long acting insulin and a pancredinal peptide comprising an insulin and a pancredinal peptide belonging to a physiologically active peptide, and an albumin-free stabilizer, wherein the stabilizer The invention comprises a buffering agent, a sugar alcohol, a nonionic surfactant and an isotonic agent; and a preparation method of the liquid preparation. The liquid preparation of the present invention contains no human serum albumin and a potential toxic factor of the human body, and thus has excellent storage stability for a high concentration of insulin conjugate and a pancredinal peptide conjugate without risk of virus contamination. |