http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201410679-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D487-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-32 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P23-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-18 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-551 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-506 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4985 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D487-04 |
| filingDate | 2013-08-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_571a56049700f9445fe2bc753adf02d4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fa98399f31151b94885ad56af2aae10a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c7bf89a5bbfaddf318eccb027b27399 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_209259f9f93ce12923b6dae8f91c4a70 |
| publicationDate | 2014-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201410679-A |
| titleOfInvention | Piperido[1,2-a]indol-1-one and [1,4]diazepine[1,2-a]indol-1-one |
| abstract | The present invention relates to a compound of the formula I wherein R1 is hydrogen, halogen, lower alkyl, lower alkoxy, lower alkoxy or cyano substituted by halogen; R2 hydrogen, low carbon a number of alkyl or a lower alkyl group substituted by halogen; R3 is phenyl, benzo[1,3]dioxolyl, 2,3-dihydro-benzofuran-5-yl or 5 And 6 member heteroaryl, wherein the phenyl group and the 5 member and 6 membered heteroaryl group may be substituted by one or more substituents selected from the group consisting of a cyano group, a nitro group, an amine group and a lower carbon dialkyl group. Amino, lower alkyl alkylsulfonyl, lower alkoxy, lower alkoxy substituted by halogen, halogen, lower alkyl, lower alkyl substituted by halogen or by hydroxy Substituted lower alkyl group; X-type -CH(lower alkyl)-, -CH2-, -CH2CH2- or -CH(lower alkyl)CH2-; R-hydrogen or lower alkyl n is a 1 or 2; or a pharmaceutically acceptable acid addition salt thereof, relating to its racemic mixture or to its corresponding mirror image isomer and/or optical isomer. These compounds are useful in the treatment of schizophrenia, obsessive-compulsive personality disorder, severe depression, bipolar disorder, anxiety, normal aging, epilepsy, retinal degeneration, traumatic brain injury, spinal injury, post-traumatic stress disorder, panic disorder, Parkinson's disease Parkinson's disease, dementia, Alzheimer's disease, mild cognitive impairment, chemo-induced cognitive dysfunction, Down syndrome, autism spectrum disorder, deafness, tinnitus , Spinocerebellar disorders, amyotrophic lateral sclerosis, multiple sclerosis, Huntington's disease, stroke, radiation therapy, chronic stress, abuse of neurostimulants (eg alcohol, opiates) (opiates), methamphetamine, phencyclidine, and cocaine. |
| priorityDate | 2012-08-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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